Lindsay Applegate (1808-1892) pioneered Oregon's Applegate Trail with his brothers Charles and Jesse in 1843. Subsequently Applegate became a U.S. government agent for the Modoc and Klamath Indians. The Lindsay Applegate papers contain newspaper clippings related to the Applegate family; letters (1863-1891); and reports, vouchers and other administrative documents relating to Applegate's work as Subagent at Ft. Klamath (1866-1872).